Our previous study had demonstrated cytotoxicity of gallic acid on testicular cells with increasing the intracellular production of hydrogen peroxide. In the present study, the Panax ginseng root aqueous extract showed the cytoprotective effect on gallic acid-induced toxicity in TM3 mouse Leydig cells with decreasing the intracellular production of hydrogen peroxide. © 2007 Elsevier B.V. All rights reserved.
Cytoprotective effect; Gallic acid; Leydig cell; Panax ginseng
EMTREE drug terms: gallic acid; ginseng extract; hydrogen peroxide
EMTREE medical terms: animal cell; aqueous solution; article; cell protection; controlled study; cytotoxicity; drug effect; ginseng; Leydig cell; mouse; nonhuman; plant root; priority journal
MeSH: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Gallic Acid; Hydrogen Peroxide; Leydig Cells; Male; Mice; Panax; Phytotherapy; Plant Extracts; Plant Roots; Protective Agents
Medline is the source for the MeSH terms of this document.
Species Index: Panax ginseng
Chemicals and CAS Registry Numbers: gallic acid, 149-91-7; hydrogen peroxide, 7722-84-1;Gallic Acid, 149-91-7; Hydrogen Peroxide, 7722-84-1; Plant Extracts; Protective Agents