Abstract

Our previous study had demonstrated cytotoxicity of gallic acid on testicular cells with increasing the intracellular production of hydrogen peroxide. In the present study, the Panax ginseng root aqueous extract showed the cytoprotective effect on gallic acid-induced toxicity in TM3 mouse Leydig cells with decreasing the intracellular production of hydrogen peroxide. © 2007 Elsevier B.V. All rights reserved.

Author keywords

Cytoprotective effect; Gallic acid; Leydig cell; Panax ginseng

Indexed keywords

EMTREE drug terms: gallic acid; ginseng extract; hydrogen peroxide

EMTREE medical terms: animal cell; aqueous solution; article; cell protection; controlled study; cytotoxicity; drug effect; ginseng; Leydig cell; mouse; nonhuman; plant root; priority journal

MeSH: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Gallic Acid; Hydrogen Peroxide; Leydig Cells; Male; Mice; Panax; Phytotherapy; Plant Extracts; Plant Roots; Protective Agents
Medline is the source for the MeSH terms of this document.

Species Index: Panax ginseng

Chemicals and CAS Registry Numbers: gallic acid, 149-91-7; hydrogen peroxide, 7722-84-1;Gallic Acid, 149-91-7; Hydrogen Peroxide, 7722-84-1; Plant Extracts; Protective Agents