경희대학교 한의과대학 배현수 교수 연구실

대표논문 게시판 내 결과

• Bee venom phospholipase A2 ameliorates Alzheimer’s disease pathology in Aβ vaccination treatment without inducing neuro-infammation in a 3xTg-AD mouse model 새창

     DOI  https://doi.org/10.1038/s41598-018-35030-1  JOURNAL  SCIENTIFIC REPORTS  TITLE  Bee venom phospholipase A2 ameliorates Alzheimer’s disease pathology in Aβ vaccination treatment without inducing neur…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2018-11-27 13:51:16
• A standardized herbal extract PM014 ameliorates pulmonary fbrosis by suppressing the TGF-β1 pathway 새창

     DOI  https://doi.org/10.1038/s41598-018-35320-8 2  JOURNAL  SCIENTIFIC REPORTS  TITLE  A standardized herbal extract PM014 ameliorates pulmonary fbrosis by suppressing the TGF-β1 pathway 

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2018-11-16 15:05:12
• Melittin suppresses tumor progression by regulating tumorassociated macrophages in a Lewis lung carcinoma mouse model 새창

     DOI  .  JOURNAL  Oncotarget  TITLE  Melittin suppresses tumor progression by regulating tumorassociated macrophages in a Lewis lung carcinoma mouse model 

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2017-07-04 09:08:50
• Standardized Herbal Formula PM014 Inhibits Radiation-Induced Pulmonary Inflammation in Mice 새창

     DOI  10.1038/srep45001  JOURNAL  SCIENTIFIC REPORTS  TITLE  Standardized Herbal Formula PM014 Inhibits Radiation-Induced Pulmonary Inflammation in Mice 

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2017-03-25 16:01:57
• Adenovirus-mediated Foxp3 expression in lung epithelial cells reduces airway inflammation in ovalbumin and cockroach-induced asthma model 새창

     DOI  10.1038/emm.2016.83  JOURNAL  Experimetal & Molecular Medicine  TITLE  Adenovirus-mediated Foxp3 expression in lung epithelial cells reduces airway inflammation in ovalbumin and cockroach-i…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2016-09-22 19:50:08
• Bee venom phospholipase A2 ameliorates motor dysfunction and modulates microglia activation in Parkinson’s disease alpha-synuclein transgenic mice 새창

     DOI  10.1038/emm.2016.49  JOURNAL  Experimental & Molecular Medicine  TITLE  Bee venom phospholipase A2 ameliorates motor dysfunction and modulates microglia activation in Parkinson’s disease al…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2016-07-12 14:38:37
• Bee Venom Phospholipase A2, a Novel Foxp3+ Regulatory T Cell Inducer, Protects Dopaminergic Neurons by Modulating Neuroinflammatory Responses in a Mouse Model of Parkinson’s Disease 새창

  Foxp3-expressing CD4+ regulatory T cells (Tregs) are vital for maintaining immune tolerance in animal models of various immune diseases. In the present study, we demonstrated that bee venom phospholipase A2 (bvPLA2) is the major BV compound capable of inducing Treg expansion and promotes the surviva…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2015-11-16 09:04:30
• Neuro-protective effects of bee venom by suppression of neuroinflammatory responses in a mouse model of Parkinson's disease: Role of regulatory T cells 새창

  Abstract In the present study, we sought to determine whether bee venom (BV) promotes the survival of dopaminergic (DA) neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson’s disease (PD). Treatment with BV prevented degeneration of DA neurons in the substanti…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2013-08-19 22:02:14
• Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells 새창

  Abstract CD4+CD25+ regulatory T (Treg) cells play crucial roles in the host response to tumors. Increasing evidence supports the existence of elevated numbers of Treg cells in solid tumors and hematologic malignancies. In this study, the effects of methyl gallate …

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2013-08-19 22:14:24
• Foxp3 is a novel repressor of microglia activation 새창

  Abstract Forkhead transcription factor3 (Foxp3) is critical for generating CD4+CD25+ regulatory T cells. However, its role in microglia has not been identified. Here, we show that Foxp3 is expressed in microglia and is upregulated upon activation. In Foxp3 mutant mice (Foxp3sf), microglia relea…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2013-08-19 22:16:06