경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
2 전체검색 결과
- 게시판
- 1개
- 게시물
- 55개
1/6 페이지 열람 중
기타논문 게시판 내 결과
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Enhanced Therapeutic Effect of Optimized Melittin-dKLA, a Peptide Agent Targeting M2-like Tumor-Associated Macrophages in Triple-Negative Breast Cancer
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DOI https://doi.org/10.3390/ijms232415751 JOURNAL International Journal of Molecular Sciences TITLE Enhanced Therapeutic Effect of Optimized Melittin-dKLA, a Peptide Agent Targeting M2-like Tumor-As…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-12-16 14:32:59 -
TAMpepK Suppresses Metastasis through the Elimination of M2-Like Tumor-Associated Macrophages in Triple-Negative Breast Cancer
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Abstract: Triple-negative breast cancer (TNBC) accounts for approximately 10–15% of all breast cancer cases and is characterized by high invasiveness, high metastatic potential, relapse proneness, and poor prognosis. M2-like tumor-associated macrophages (TAMs) contribute to tumorigenesis and are pro…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 15:18:46 -
The Responsiveness of Bee Venom Phospholipase A2 on Regulatory T Cells Correlates with the CD11c+CD206+Population in Human Peripheral Blood Mononuclear Cells
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Abstract: Bee venom phospholipase A2 (bvPLA2) has been reported to have therapeutic effects such as neuroprotection, anti-inflammation, anti-nociception, anti-cancer properties, caused by increasing regulatory T cells (Tregs). The mechanism of Tregs modulation by bvPLA2 has been …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:53:48 -
Targeting of adipose tissue macrophages by bee venom phospholipase A2 attenuates high-fat diet-induced obesity
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Abstract Background/objectives Adipose tissue macrophages (ATMs) exist in either the M1 or M2 form. The anti-inflammatory M2 ATMs accumulate in lean individuals, whereas the pro-inflammatory M1 ATMs accumulate in obese individuals. Bee venom phospholipase A2 (bvPLA2), a major co…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:41:51 -
Magnoliae Cortex Alleviates Muscle Wasting by Modulating M2 Macrophages in a Cisplatin-Induced Sarcopenia Mouse Model
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Abstract: Cachexia causes high mortality, low quality of life, and rapid weight loss in cancer patients. Sarcopenia, a condition characterized by the loss of muscle, is generally present in cachexia and is associated with inflammation. M2 macrophages, also known as an anti-inflam…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:31:43 -
Bee venom phospholipase A2 alleviates collagen‑induced polyarthritis by inducing Foxp3+ regulatory T cell polarization in mice
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The mechanism underlying bee venom (BV) therapy is still controversial, with opinions ranging from constituent-based pharmacological action to homeopathic-like activity. The purpose of this study was to examine whether BV phospholipase A2 (bvPLA2), an enzymatic component of BV, i…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:25:21 -
Bee Venom Phospholipase A2 Induces Regulatory T Cell Populations by Suppressing Apoptotic Signaling Pathway
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Abstract: Bee venom phospholipase A2 is a lipolytic enzyme in bee venom that catalyzes hydrolysis of the sn-2 ester bond of membrane phospholipids to produce free fatty acid and lysophospholipids.Current evidence suggests that bee venom phospholipase A2 (bvPLA2) induces regulatory T cell expansion…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-10-29 15:25:36 -
Bee Venom Phospholipase A2 Ameliorates Atherosclerosis by Modulating Regulatory T Cells
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Abstract: Atherosclerosis is a chronic inflammatory disease caused by lipids and calcareous accumulations in the vascular wall due to an inflammatory reaction. Recent reports have demonstrated that regulatory T (Treg) cells have an important role as a new treatment for atherosclerosis. This studys…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-10-29 15:11:47 -
Bee Venom Phospholipase A2 Induces Regulatory T Cell Populations by Suppressing Apoptotic Signaling Pathway
새창
Abstract: Bee venom phospholipase A2 is a lipolytic enzyme in bee venom that catalyzes hydrolysis of the sn-2 ester bond of membrane phospholipids to produce free fatty acid and lysophospholipids. Current evidence suggests that bee venom phospholipase A2 (bvPLA2) induces regulato…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-04-10 11:52:25 -
Comparison of the Protective Effects of Bee Venom Extracts with Varying PLA2 Compositions in a Mouse Model of Parkinson’s Disease
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AbstractBee venom contains a number of pharmacologically active components, including enzymes and polypeptides such as phospholipase A2 (PLA2) and melittin, which have been shown to exhibit therapeutic benefits, mainly via attenuation of inflammation, neurotoxicity, and nociception. The …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2019-07-26 15:19:21