경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
2 전체검색 결과
- 게시판
- 8개
- 게시물
- 123개
2/13 페이지 열람 중
대표논문 게시판 내 결과
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Bee Venom Phospholipase A2, a Novel Foxp3+ Regulatory T Cell Inducer, Protects Dopaminergic Neurons by Modulating Neuroinflammatory Responses in a Mouse Model of Parkinson’s Disease
새창
Foxp3-expressing CD4+ regulatory T cells (Tregs) are vital for maintaining immune tolerance in animal models of various immune diseases. In the present study, we demonstrated that bee venom phospholipase A2 (bvPLA2) is the major BV compound capable of inducing Treg expansion and promotes the surviva…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2015-11-16 09:04:30 -
Phospholipase A2 inhibits cisplatin-induced acute kidney injury by modulating regulatory T cells by the CD206 mannose receptor
새창
DOI 10.1038/ki.2015.147 JOURNAL Kidney International TITLE Phospholipase A2 inhibits cisplatin-induced acute kidney injury by modulating regulatory T cells by the CD206 mannose receptor …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2015-06-04 15:01:32 -
Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells
새창
Abstract CD4+CD25+ regulatory T (Treg) cells play crucial roles in the host response to tumors. Increasing evidence supports the existence of elevated numbers of Treg cells in solid tumors and hematologic malignancies. In this study, the effects of methyl gallate …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2013-08-19 22:14:24 -
CD4+ CD25+ regulatory T cells attenuate cisplatin-induced nephrotoxicity in mice
새창
Abstract Nephrotoxicity limits the use of cisplatin, a widely used chemotherapeutic agent for treatment of various malignancies. Overall, CD4+ T cells mediate cisplatin-induced renal injury; however, the CD4+CD25+ regulatory T-cell subset (CD4+CD25+ Treg) has broad suppressive effects …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2013-08-19 22:10:57 -
The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis
새창
Abstract Nuclear factor of activated T cells (NFAT) transcription factors regulate gene expression in lymphocytes and control cardiac valve formation. Here, we report that NFATp regulates chondrogenesis in the adult animal. In mice lacking NFATp, resident cel…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2013-08-19 22:26:08
기타논문 게시판 내 결과
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Enhanced Therapeutic Effect of Optimized Melittin-dKLA, a Peptide Agent Targeting M2-like Tumor-Associated Macrophages in Triple-Negative Breast Cancer
새창
DOI https://doi.org/10.3390/ijms232415751 JOURNAL International Journal of Molecular Sciences TITLE Enhanced Therapeutic Effect of Optimized Melittin-dKLA, a Peptide Agent Targeting M2-like Tumor-As…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-12-16 14:32:59 -
TAMpepK Suppresses Metastasis through the Elimination of M2-Like Tumor-Associated Macrophages in Triple-Negative Breast Cancer
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Abstract: Triple-negative breast cancer (TNBC) accounts for approximately 10–15% of all breast cancer cases and is characterized by high invasiveness, high metastatic potential, relapse proneness, and poor prognosis. M2-like tumor-associated macrophages (TAMs) contribute to tumorigenesis and are pro…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 15:18:46 -
The Responsiveness of Bee Venom Phospholipase A2 on Regulatory T Cells Correlates with the CD11c+CD206+Population in Human Peripheral Blood Mononuclear Cells
새창
Abstract: Bee venom phospholipase A2 (bvPLA2) has been reported to have therapeutic effects such as neuroprotection, anti-inflammation, anti-nociception, anti-cancer properties, caused by increasing regulatory T cells (Tregs). The mechanism of Tregs modulation by bvPLA2 has been …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:53:48 -
Targeting of adipose tissue macrophages by bee venom phospholipase A2 attenuates high-fat diet-induced obesity
새창
Abstract Background/objectives Adipose tissue macrophages (ATMs) exist in either the M1 or M2 form. The anti-inflammatory M2 ATMs accumulate in lean individuals, whereas the pro-inflammatory M1 ATMs accumulate in obese individuals. Bee venom phospholipase A2 (bvPLA2), a major co…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:41:51 -
Magnoliae Cortex Alleviates Muscle Wasting by Modulating M2 Macrophages in a Cisplatin-Induced Sarcopenia Mouse Model
새창
Abstract: Cachexia causes high mortality, low quality of life, and rapid weight loss in cancer patients. Sarcopenia, a condition characterized by the loss of muscle, is generally present in cachexia and is associated with inflammation. M2 macrophages, also known as an anti-inflam…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:31:43