경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
2 전체검색 결과
- 게시판
- 8개
- 게시물
- 123개
3/13 페이지 열람 중
기타논문 게시판 내 결과
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Bee venom phospholipase A2 alleviates collagen‑induced polyarthritis by inducing Foxp3+ regulatory T cell polarization in mice
새창
The mechanism underlying bee venom (BV) therapy is still controversial, with opinions ranging from constituent-based pharmacological action to homeopathic-like activity. The purpose of this study was to examine whether BV phospholipase A2 (bvPLA2), an enzymatic component of BV, i…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:25:21 -
Bee Venom Phospholipase A2 Induces Regulatory T Cell Populations by Suppressing Apoptotic Signaling Pathway
새창
Abstract: Bee venom phospholipase A2 is a lipolytic enzyme in bee venom that catalyzes hydrolysis of the sn-2 ester bond of membrane phospholipids to produce free fatty acid and lysophospholipids.Current evidence suggests that bee venom phospholipase A2 (bvPLA2) induces regulatory T cell expansion…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-10-29 15:25:36 -
Bee Venom Phospholipase A2 Ameliorates Atherosclerosis by Modulating Regulatory T Cells
새창
Abstract: Atherosclerosis is a chronic inflammatory disease caused by lipids and calcareous accumulations in the vascular wall due to an inflammatory reaction. Recent reports have demonstrated that regulatory T (Treg) cells have an important role as a new treatment for atherosclerosis. This studys…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-10-29 15:11:47 -
Bee Venom Phospholipase A2 Induces Regulatory T Cell Populations by Suppressing Apoptotic Signaling Pathway
새창
Abstract: Bee venom phospholipase A2 is a lipolytic enzyme in bee venom that catalyzes hydrolysis of the sn-2 ester bond of membrane phospholipids to produce free fatty acid and lysophospholipids. Current evidence suggests that bee venom phospholipase A2 (bvPLA2) induces regulato…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-04-10 11:52:25 -
Comparison of the Protective Effects of Bee Venom Extracts with Varying PLA2 Compositions in a Mouse Model of Parkinson’s Disease
새창
AbstractBee venom contains a number of pharmacologically active components, including enzymes and polypeptides such as phospholipase A2 (PLA2) and melittin, which have been shown to exhibit therapeutic benefits, mainly via attenuation of inflammation, neurotoxicity, and nociception. The …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2019-07-26 15:19:21 -
Prophylactic Effects of Bee Venom Phospholipase A2 in Lipopolysaccharide-Induced Pregnancy Loss
새창
AbstractSpontaneous abortion represents a common form of embryonic loss caused by early pregnancy failure. In the present study, we investigated the prophylactic effects of bee venom phospholipase A2 (bvPLA2), a regulatory T cell (Treg) inducer, on a lipopolysaccharide (LPS)-induced abortion mouse…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2019-07-26 15:00:28 -
Comparison of Administration Routes on the Protective Effects of Bee Venom Phospholipase A2 in a Mouse Model of Parkinson’s Disease
새창
Parkinson’s disease (PD) is the second most common neurodegenerative disorder worldwide. Progressive loss of dopaminergic neurons in the substantia nigra (SN) and their synaptic terminal connections in the striatum are main characterizations of PD. Although many efforts have been made to develop the…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2018-11-16 15:21:01 -
Bee Venom Phospholipase A2 Alleviate House Dust Mite-Induced Atopic Dermatitis-Like Skin Lesions by the CD206 Mannose Receptor
새창
Abstract: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by highly pruritic, erythematous, and eczematous skin plaques. We previously reported that phospholipase A2 (PLA2) derived from bee venom alleviates AD-like skin lesions induced by 2,4-dinitroch…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2018-11-16 15:10:46 -
Curcumin attenuates the scurfy-induced immune disorder, a model of IPEX syndrome, with inhibiting Th1/Th2/Th17 responses in mice
새창
a b s t r a c t Background: Immunodysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX) is a lethal autoimmune disease caused by mutations in the Foxp3 gene scurfin (scurfy). Immunosuppressive therapy for IPEX patients has been generally ineffective and has caused severe side effect…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2017-07-26 09:01:35 -
Bee Venom Phospholipase A2 Ameliorates House Dust Mite Extract Induced Atopic Dermatitis Like Skin Lesions in Mice
새창
Abstract: Atopic dermatitis (AD) is a biphasic inflammatory skin disease that is provoked byepidermal barrier defects, immune dysregulation, and increased skin infections. Previously, we havedemonstrated that bvPLA2 evoked immune tolerance by inducing regulatory T cells (Treg), and thusalleviated Th…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2017-02-21 16:39:32