경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
2 전체검색 결과
- 게시판
- 1개
- 게시물
- 55개
3/6 페이지 열람 중
기타논문 게시판 내 결과
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Bee Venom Phospholipase A2 Protects against Acetaminophen-Induced Acute Liver Injury by Modulating Regulatory T Cells and IL-10 in Mice
새창
Abstract The aim of this study was to investigate the protective effects of phospholipase A2 (PLA2) from bee venom against acetaminophen-induced hepatotoxicity through CD4+CD25+Foxp3+ T cells (Treg) in mice. Acetaminophen (APAP) is a widely used antipyretic and analgesic, but an acute or cumulative…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-26 10:43:48 -
Metergoline inhibits the neuronal Nav1.2 voltage-dependent Na+ channels expressed in Xenopus oocytes
새창
Abstract Aim:Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors. The aim of this study was to investigate the regulatory effects of metergoline on the neuronal Nav1.2 voltage-dependent Na+ channels in vitro.Methods:Xenopus oocytes were injec…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 01:11:26 -
A novel synthetic compound 4-Acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c] pyran-1,8-dione inhibits the production of nitric oxide and proinflammatory cytokines Via the NF-κB pathway in lipopolysaccharide-activated microglia cells
새창
Abstract Previously, we discovered a new compound, 1H,8H-Pyrano[3,4-c]pyran-1,8- dione (PPY), from Vitex rotundifolia L. and evaluated its anti-inflammatory and anti-asthmatic effects. In this study, we synthesized a new, modified compound 4-acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c]pyran-1,8-d…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 00:08:17 -
Bee venom mitigates cisplatin-induced nephrotoxicity by regulating CD4 +CD25+Foxp3+ regulatory T cells in mice
새창
Abstract Cisplatin is used as a potent anticancer drug, but it often causes nephrotoxicity. Bee venom (BV) has been used for the treatment of various inflammatory diseases, and its renoprotective action was shown in NZB/W mice. However, little is known about whether BV has beneficial effects on cis…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 00:06:37 -
Bee venom attenuates experimental autoimmune encephalomyelitis through direct effets on CD4+CD25+FOXP3+ T cells
새창
Abstract Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system that leads to substantial disability through deficits of sensation and of motor, autonomic, and neuro-cognitive function. Many clinical and pathological features of experimental autoimmune encephalomyel…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 00:00:19 -
Cd4+cd25+ regulatory t cell depletion modulates anxiety and depression-like behaviors in mice
새창
Abstract Stress has been shown to suppress immune function and increase susceptibility to inflammatory disease and psychiatric disease. CD4+CD25+ regulatory T (Treg) cells are prominent in immune regulation. This study was conducted to determine if anti-CD25 antibody (Ab) mediated depletion of Treg…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 23:49:23 -
Electroacupuncture attenuates ovalbumin-induced allergic asthma via modulating CD4 +CD25 + regulatory T cells
새창
Abstract A mouse pulmonary hypersensitivity experimental model that mimics human asthma was developed, and electroacupuncture (EA) treatment was shown to reduce allergic inflammatory processes. In addition, we also assessed whether the beneficial effects of EA on allergic asthma could be correlated…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 23:43:38 -
Safety and efficacy assessment of standardized herbal formula PM012
새창
Abstract Background: This study was conducted to evaluate the efficacy of the herbal formula PM012 on an Alzheimer's disease model, human presenilin 2 mutant transgenic mice (hPS2m), and also to evaluate the toxicity of PM012 in Sprague-Dawely rats after 4 or 26 weeks treatment with repeated o…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:43:52 -
Anti-diabetic effect of standardized herbal formula PM021 consisting of Mori Folium and Aurantii Fructus on type II diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats
새창
Abstract PM021, which consists of two herbal components, Mori Folium and Aurantii Fructus, is routinely used to treat diabetes in Korea. In this study, the anti-diabetic effect of PM021 on an animal model of developing type 2 diabetes of Otsuka Long-Evans Tokushima Fatty (OLETF) rats was investigat…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:29:03 -
The genome-wide expression profile of 1,2,3,4,6-penta-O-galloyl-ß-D- glucose-treated MDA-MB-231 breast cancer cells: Molecular target on cancer metabolism
새창
Abstract 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG), a polyphenolic compound isolated from Rhus chinensis Mill. PGG has been known to have anti-tumor, anti-angiogenic and anti-diabetic activities. The present study revealed another underlying molecular target of PGG in MDA-MB-231 breast cancer …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:27:49