경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
3 전체검색 결과
- 게시판
- 1개
- 게시물
- 26개
2/3 페이지 열람 중
기타논문 게시판 내 결과
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The genome-wide expression profile of 1,2,3,4,6-penta-O-galloyl-ß-D- glucose-treated MDA-MB-231 breast cancer cells: Molecular target on cancer metabolism
새창
Abstract 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG), a polyphenolic compound isolated from Rhus chinensis Mill. PGG has been known to have anti-tumor, anti-angiogenic and anti-diabetic activities. The present study revealed another underlying molecular target of PGG in MDA-MB-231 breast cancer …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:27:49 -
Melatonin promotes puromycin-induced apoptosis with activation of caspase-3 and 5′-adenosine monophosphate-activated kinase-alpha in human leukemia HL-60 cells
새창
Abstract Melatonin, a naturally occurring molecule, is produced by the pineal gland in a circadian manner to regulate biologic rhythms in humans. Recent studies report that melatonin may be an attractive candidate as an anticancer agent or for combined therapy because of its antioxidant, oncostatic…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:23:10 -
1,2,3,4,6-Penta-O-galloyl-beta-D-glucose reduces renal crystallization and oxidative stress in a hyperoxaluric rat model
새창
Abstract Adhesion of calcium oxalate (CaOx) crystals to kidney cells may be a key event in the pathogenesis of kidney stones associated with marked hyperoxaluria. Previously, we found that 1,2,3,4,6-penta-O-galloyl-Β-D-glucose (PGG), isolated from a traditional medicinal herb, reduced CaOx crystal …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:18:34 -
The genome-wide expression profile of Curcuma longa-treated cisplatin-stimulated HEK293 cells
새창
Abstract WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • High doses of cisplatin more effectively suppress cancer, but high dose therapy is limited by nephrotoxic side effects, Nephrotoxicity is of critical concern during the early stages of drug development when selecting new drug candidates. Curcuma l…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:07:14 -
Regulation of the 5-HT3A receptor-mediated current by alkyl 4-hydroxybenzoates isolated from the seeds of Nelumbo nucifera
새창
Abstract Four known alkyl 4-hydroxybenzoates, i.e., methyl 4-hydroxybenzoate (1), ethyl 4-hydroxybenzoate (2), propyl 4-hydroxybenzoate (3), and butyl 4-hydroxybenzoate (4), were isolated from the seeds of Nelumbo nucifera GAERTNER (Nymphaeaceae) for the first time. The structures of the isolates w…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:03:55 -
Foxp3 is a novel repressor of microglia activation
새창
Abstract Forkhead transcription factor3 (Foxp3) is critical for generating CD4 +CD25+ regulatory T cells. However, its role in microglia has not been identified. Here, we show that Foxp3 is expressed in microglia and is upregulated upon activation. In Foxp3 mutant mice (Foxp3sf), microglia release …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:01:27 -
Compound K inhibits basic fibroblast growth factor-induced angiogenesis via regulation of p38 mitogen activated protein kinase and AKT in human umbilical vein endothelial cells
새창
Abstract Compound K (CK; 20-0-β-D-glucopyranosyl-20(5)-protopanaxadiol), an active ginseng saponin metabolite, exerts anticancer activity via apoptosis induction in various cancers. In the present study, we investigated the anti-angiogenic activity of CK and its molecular mechanisms in human umbili…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 20:20:59 -
Effects of protostane-type triterpenoids on the 5-HT3A receptor-mediated ion current in Xenopus oocytes
새창
Abstract Alisol derivatives are unique protostane-type triterpenoid compounds that are isolated from Alismatis rhizoma, which is a well-known traditional medicine in East Asia. In the present study, we investigated the effects of protostane-type triterpenoids (AA, Alisol A; AB, Alisol B; AB-ac, Ali…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 20:18:28 -
The genome-wide expression profile of Paeonia suffruticosa-treated cisplatin-stimulated HEK 293 cells
새창
Abstract The root cortex of Paeonia suffruticosa Andrews (PS) is a crude Chinese drug used in many traditional prescriptions. This study was conducted to evaluate the recovery mechanisms induced by PS in HEK 293 cells treated with cisplatin. Previous studies revealed that 1 μg/ml PS treatment showe…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 19:17:48 -
Inulin increases glucose transport in c2c12 myotubes and hepg2 cells via activation of amp-activated protein kinase and phosphatidylinositol 3-kinase pathways
새창
Abstract Inulin, a naturally occurring, functional food ingredient found in various edible plants, has been reported to exert potential health benefits, including decreased risk of colonic diseases, non-insulin-dependent diabetes, obesity, osteoporosis, and cancer. However, the mechanism of the ant…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 19:16:18