경희대학교 한의과대학 배현수 교수 연구실

기타논문 게시판 내 결과

• Evaluation of the Efficacy and Safety of the Herbal Formula PM014 in a Cisplatin- and Paclitaxel-Treated Tumor-Bearing Mouse Model 새창

  AbstractPM014 (HL301) is a standardized herbal mixture derived from a traditional Korean medicine, Chung-Sang-Bo-Ha-Tang. Previously, we reported that PM014 treatment significantly suppressed pulmonary fibrosis, one of the frequent adverse effects of anticancer therapy in lung cancer. Before the cli…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-10-29 15:19:57
• Standardized herbal extract PM014 alleviates fine dust-induced lung inflammation in mice 새창

  Background: Fine dust penetrates deep into the human alveoli, and the fine dust accumulated in the bronchus and lungs can directly trigger various respiratory diseases. PM014 (HL301) is the herbal extract derived from the herbal medicine Chung-Sang-Bo-Ha-Tang which is used for the treatment of lun…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-10-29 15:05:57
• Corni fructus ameliorates menopause symptom in 4-vinylcyclohexene diepoxide 새창

  Menopause is considered to mean falling levels of ovarian estradiol and progesterone. Menopause syndrome can lead to hot flashes, headaches, and depression etc. Corni Fructus (CF) was used as a therapeutic herbal medicine for treating various diseases such as pain, diabetic nephropathy and tuberculo…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2018-11-16 15:18:20
• Cd4+cd25+ regulatory t cell depletion modulates anxiety and depression-like behaviors in mice 새창

  Abstract Stress has been shown to suppress immune function and increase susceptibility to inflammatory disease and psychiatric disease. CD4+CD25+ regulatory T (Treg) cells are prominent in immune regulation. This study was conducted to determine if anti-CD25 antibody (Ab) mediated depletion of Tr…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2013-08-19 22:04:20
• The effects of the standardized herbal formula PM014 on pulmonary inflammation and airway responsiveness in a murine model of cockroach allergen-induced asthma 새창

  Abstract Ethnopharmacological relevance PM014 is a modified form of the Chung-Sang-Bo-Ha-Tang (CSBHT) herbal formula that has been used to treat chronic pulmonary diseases in Korea for centuries. Previously, we developed a formulation of PM014 based on a series of in vitro and in vivo screening eff…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 01:16:54
• Pogostemon Cabin prevents the MPTP-induced loss of dopaminergic neurons by inhibiting CD4+ T cell infiltration in the brain 새창

  Abstract Parkinson’s disease (PD) involves the neurodegeneration of dopaminergic neurons, which is accompanied by neuroinflammation in the substantia nigra (SN). Mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) exhibit microglial activation-induced inflammation as well as DA ne…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 00:57:51
• Thirteen-week study of PM014 subchronic oral toxicity in rats 새창

  Abstract PM014 is a modified herbal formula based on Chung-Sang-Bo-Ha-Tang, which is a well-known prescription drug used for curing various inflammatory pulmonary diseases. We previously showed that PM014 attenuated lung inflammation in a murine model of chronic obstructive pulmonary disease (COPD)…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 00:56:16
• A synthetic compound, 4-acetyl-3-methyl-6-(3,4,5-trimethoxyphenyl)pyrano[3, 4-c]pyran-1,8-dione, ameliorates ovalbumin-induced asthma 새창

  Abstract Eosinophilia is one of the characteristic signs of allergic inflammation. Massive migration of eosinophils to the airways can cause epithelial tissue injury, contraction of airway smooth muscle and increased bronchial responsiveness. Previously, we discovered a new compound, 1H,8H-pyrano[3…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 00:32:55
• The standardized herbal formula, PM014, ameliorated cigarette smoke-induced lung inflammation in a murine model of chronic obstructive pulmonary disease 새창

  Abstract Background: In this study, we evaluated the anti-inflammatory effect of PM014 on cigarette smoke induced lung disease in the murine animal model of chronic obstructive pulmonary disease (COPD).Methods: Mice were exposed to cigarette smoke (CS) for 2 weeks to induce COPD-like lung inflammat…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 00:17:52
• A novel synthetic compound 4-Acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c] pyran-1,8-dione inhibits the production of nitric oxide and proinflammatory cytokines Via the NF-κB pathway in lipopolysaccharide-activated microglia cells 새창

  Abstract Previously, we discovered a new compound, 1H,8H-Pyrano[3,4-c]pyran-1,8- dione (PPY), from Vitex rotundifolia L. and evaluated its anti-inflammatory and anti-asthmatic effects. In this study, we synthesized a new, modified compound 4-acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c]pyran-1,8-d…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 00:08:17