경희대학교 한의과대학 배현수 교수 연구실

기타논문 게시판 내 결과

• A novel synthetic compound 4-Acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c] pyran-1,8-dione inhibits the production of nitric oxide and proinflammatory cytokines Via the NF-κB pathway in lipopolysaccharide-activated microglia cells 새창

  Abstract Previously, we discovered a new compound, 1H,8H-Pyrano[3,4-c]pyran-1,8- dione (PPY), from Vitex rotundifolia L. and evaluated its anti-inflammatory and anti-asthmatic effects. In this study, we synthesized a new, modified compound 4-acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c]pyran-1,8-d…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-17 00:08:17
• Screening herbal medicines for the recovery of alpha-synuclein-induced Parkinson's disease model of yeast 새창

  Abstract The goal of this study was quantitatively determine the recovery effects of herbal medicines (HM) on the alpha-synuclein (α-Syn)-induced Parkinson's disease. In the present study, the detoxification effects of 270 HM in a yeast model of Parkinson's disease that had been damaged b…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 23:58:47
• Phenelzine (monoamine oxidase inhibitor) increases production of nitric oxide and proinflammatory cytokines via the NF-κB pathway in lipopolysaccharide-activated microglia cells 새창

  Abstract Phenelzine is a potent monoamine oxidase inhibitor that is used in patients with depression. It is also well known that nitric oxide (NO) synthase inhibitors show preclinical antidepressant-like properties, which suggests that NO is involved in the pathogenesis of depression. The purpose o…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 23:55:05
• The effects of Foxp3 on gene expression profiles in activated microglial cells 새창

  Abstract Microglia constitutes the first line of defense against infection and injury in the brain. We previously demonstrated that activated microglia express the Foxp3 gene. However, the role of Foxp3 in cells other than Treg is generally unknown. Therefore, this study was conducted to determine …

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 23:40:52
• Microarray analysis of the gene expression profile of HMC-1 mast cells following Schizonepeta tenuifolia Briquet treatment 새창

  Abstract It has long been believed that mast cells play a crucial role in the development of many physiological changes during immediate allergic responses. This study was conducted to evaluate the anti-inflammation mechanism of. Schizonepeta tenuifolia (ST) extract and ST purified chemicals on the…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:52:07
• The comparative analysis of in vivo and in vitro transcriptome data based on systems biology 새창

  Abstract We investigated whether an in vitro cellbased system can represent toxicity of an in vivo organ using gene expression profiles. We performed an analysis of differentially expressed transcripts, pathway analysis, and Gene Ontology (GO) grouping with the toxicity-induced data following treat…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:42:06
• Effects of Atractylodes macrocephala Koidzumi rhizome on 3T3-L1 adipogenesis and an animal model of obesity 새창

  Abstract Ethnopharmacological relevance: Atractylodes macrocephala Koidzumi (AMK) is an herbal medicine traditionally used for treatment of abdominal pain, gastrointestinal disease, obesity, and related complications. Aim of the study: We investigated the effects and molecular mechanism of AMK rhiz…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:37:36
• 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose reduces renal crystallization and oxidative stress in a hyperoxaluric rat model 새창

  Abstract Adhesion of calcium oxalate (CaOx) crystals to kidney cells may be a key event in the pathogenesis of kidney stones associated with marked hyperoxaluria. Previously, we found that 1,2,3,4,6-penta-O-galloyl-Β-D-glucose (PGG), isolated from a traditional medicinal herb, reduced CaOx crystal …

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:18:34
• Antiinflammatory effects of Epimedium brevicornum water extract on lipopolysaccharide-activated RAW264.7 macrophages 새창

  Abstract Epimedium brevicornum Maxim (Berberidaceae) possesses estrogenic properties. It is one of the most widespread herbal remedies used in Oriental medicine. The present study investigated the effects of Epimedium brevicornum water extract (EB) on proinflammatory mediators secreted from lipopol…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:12:33
• Gene expression profile analysis of genes in rat hippocampus from antidepressant treated rats using DNA microarray 새창

  Abstract Background: The molecular and biological mechanisms by which many antidepressants function are based on the monoamine depletion hypothesis. However, the entire cascade of mechanisms responsible for the therapeutic effect of antidepressants has not yet been elucidated.Results: We used a gen…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:10:25