경희대학교 한의과대학 배현수 교수 연구실

기타논문 게시판 내 결과

• Enhanced Therapeutic Effect of Optimized Melittin-dKLA, a Peptide Agent Targeting M2-like Tumor-Associated Macrophages in Triple-Negative Breast Cancer 새창

     DOI  https://doi.org/10.3390/ijms232415751  JOURNAL  International Journal of Molecular Sciences  TITLE  Enhanced Therapeutic Effect of Optimized Melittin-dKLA, a Peptide Agent Targeting M2-like Tumor-As…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-12-16 14:32:59
• Particulate Matter Exacerbates the Death of Dopaminergic Neurons in Parkinson’s Disease through an Inflammatory Response 새창

  Abstract: Particulate matter (PM), a component of air pollution, has been epidemiologically associated with a variety of diseases. Recent reports reveal that PM has detrimental effects on the brain. In this study, we aimed to investigate the biological effects of ambient particles on the neurodege…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-06-16 08:38:17
• Loss of SP-A in the Lung Exacerbates Pulmonary Fibrosis 새창

  Abstract: Idiopathic pulmonary fibrosis (IPF) is a devastating and common chronic lung disease that is pathologically characterized by the destruction of lung architecture and the accumulation of extracellular matrix in the lung. Previous studies have shown an association between lung surfactant …

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-06-16 08:31:14
• Therapeutic Effect of Melittin–dKLA Targeting Tumor-Associated Macrophages in Melanoma 새창

  Abstract: Melanoma is an immunogenic tumor and a serious type of skin cancer. Tumor-associated macrophages (TAMs) express an M2-like phenotype and are involved in all stages of melanomagenesis; it is hence a promising target for cancer immunotherapy. We herein investigated whethe…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-15 10:14:59
• TAMpepK Suppresses Metastasis through the Elimination of M2-Like Tumor-Associated Macrophages in Triple-Negative Breast Cancer 새창

  Abstract: Triple-negative breast cancer (TNBC) accounts for approximately 10–15% of all breast cancer cases and is characterized by high invasiveness, high metastatic potential, relapse proneness, and poor prognosis. M2-like tumor-associated macrophages (TAMs) contribute to tumorigenesis and are pro…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 15:18:46
• The Responsiveness of Bee Venom Phospholipase A2 on Regulatory T Cells Correlates with the CD11c+CD206+Population in Human Peripheral Blood Mononuclear Cells 새창

  Abstract: Bee venom phospholipase A2 (bvPLA2) has been reported to have therapeutic effects such as neuroprotection, anti-inflammation, anti-nociception, anti-cancer properties, caused by increasing regulatory T cells (Tregs). The mechanism of Tregs modulation by bvPLA2 has been …

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:53:48
• Evaluation of the Efficacy and Safety of the Herbal Formula PM014 in a Cisplatin- and Paclitaxel-Treated Tumor-Bearing Mouse Model 새창

  AbstractPM014 (HL301) is a standardized herbal mixture derived from a traditional Korean medicine, Chung-Sang-Bo-Ha-Tang. Previously, we reported that PM014 treatment significantly suppressed pulmonary fibrosis, one of the frequent adverse effects of anticancer therapy in lung cancer. Before the cli…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-10-29 15:19:57
• Bee Venom Phospholipase A2 Ameliorates Atherosclerosis by Modulating Regulatory T Cells 새창

  Abstract: Atherosclerosis is a chronic inflammatory disease caused by lipids and calcareous accumulations in the vascular wall due to an inflammatory reaction. Recent reports have demonstrated that regulatory T (Treg) cells have an important role as a new treatment for atherosclerosis. This studys…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-10-29 15:11:47
• Comparison of the Protective Effects of Bee Venom Extracts with Varying PLA2 Compositions in a Mouse Model of Parkinson’s Disease 새창

  AbstractBee venom contains a number of pharmacologically active components, including enzymes and polypeptides such as phospholipase A2 (PLA2) and melittin, which have been shown to exhibit therapeutic benefits, mainly via attenuation of inflammation, neurotoxicity, and nociception. The …

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2019-07-26 15:19:21
• Comparison of Administration Routes on the Protective Effects of Bee Venom Phospholipase A2 in a Mouse Model of Parkinson’s Disease 새창

  Parkinson’s disease (PD) is the second most common neurodegenerative disorder worldwide. Progressive loss of dopaminergic neurons in the substantia nigra (SN) and their synaptic terminal connections in the striatum are main characterizations of PD. Although many efforts have been made to develop the…

  최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2018-11-16 15:21:01