경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
an 전체검색 결과
- 게시판
- 1개
- 게시물
- 121개
6/13 페이지 열람 중
기타논문 게시판 내 결과
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Safety and efficacy assessment of standardized herbal formula PM012
새창
Abstract Background: This study was conducted to evaluate the efficacy of the herbal formula PM012 on an Alzheimer's disease model, human presenilin 2 mutant transgenic mice (hPS2m), and also to evaluate the toxicity of PM012 in Sprague-Dawely rats after 4 or 26 weeks treatment with repeated o…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:43:52 -
The comparative analysis of in vivo and in vitro transcriptome data based on systems biology
새창
Abstract We investigated whether an in vitro cellbased system can represent toxicity of an in vivo organ using gene expression profiles. We performed an analysis of differentially expressed transcripts, pathway analysis, and Gene Ontology (GO) grouping with the toxicity-induced data following treat…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:42:06 -
T-bet deficient mice exhibit resistance to stress-induced development of depression-like behaviors
새창
Abstract T-bet, a Th1-specific T-box transcription factor, regulates Th1 development by inducing endogenous Th1 cytokines and IFN-γ. This study was conducted to determine if T-bet knockout mice exhibit resistance to stress-induced development of depression-like behaviors. The T-bet knockout mice si…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:40:10 -
Effects of Atractylodes macrocephala Koidzumi rhizome on 3T3-L1 adipogenesis and an animal model of obesity
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Abstract Ethnopharmacological relevance: Atractylodes macrocephala Koidzumi (AMK) is an herbal medicine traditionally used for treatment of abdominal pain, gastrointestinal disease, obesity, and related complications. Aim of the study: We investigated the effects and molecular mechanism of AMK rhiz…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:37:36 -
Anti-diabetic effect of standardized herbal formula PM021 consisting of Mori Folium and Aurantii Fructus on type II diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats
새창
Abstract PM021, which consists of two herbal components, Mori Folium and Aurantii Fructus, is routinely used to treat diabetes in Korea. In this study, the anti-diabetic effect of PM021 on an animal model of developing type 2 diabetes of Otsuka Long-Evans Tokushima Fatty (OLETF) rats was investigat…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:29:03 -
The genome-wide expression profile of 1,2,3,4,6-penta-O-galloyl-ß-D- glucose-treated MDA-MB-231 breast cancer cells: Molecular target on cancer metabolism
새창
Abstract 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG), a polyphenolic compound isolated from Rhus chinensis Mill. PGG has been known to have anti-tumor, anti-angiogenic and anti-diabetic activities. The present study revealed another underlying molecular target of PGG in MDA-MB-231 breast cancer …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:27:49 -
Bee venom-associated Th1/Th2 immunoglobulin class switching results in immune tolerance of NZB/W F1 murine lupus nephritis
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Abstract Background/Aims: Bee venom (BV) therapy has been used to treat inflammatory diseases including rheumatoid arthritis in humans and in experimental animals. This study was conducted to examine the therapeutic effect of BV on established lupus nephritis in New Zealand Black/White (NZB/W) F1 f…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:25:36 -
Inhibitory effects of casticin on migration of eosinophil and expression of chemokines and adhesion molecules in A549 lung epithelial cells via NF-κB inactivation
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Abstract Ethnopharmacological relevance: The fruits of Vitex rotundifolia L. have long been used for the treatment of inflammation of the respiratory tract in East Asia. Aim: To determine if casticin, one of the constituents of Vitex rotundifolia L., has anti-allergic and anti-inflammatory effects …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:24:24 -
Melatonin promotes puromycin-induced apoptosis with activation of caspase-3 and 5′-adenosine monophosphate-activated kinase-alpha in human leukemia HL-60 cells
새창
Abstract Melatonin, a naturally occurring molecule, is produced by the pineal gland in a circadian manner to regulate biologic rhythms in humans. Recent studies report that melatonin may be an attractive candidate as an anticancer agent or for combined therapy because of its antioxidant, oncostatic…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:23:10 -
1,2,3,4,6-Penta-O-galloyl-beta-D-glucose reduces renal crystallization and oxidative stress in a hyperoxaluric rat model
새창
Abstract Adhesion of calcium oxalate (CaOx) crystals to kidney cells may be a key event in the pathogenesis of kidney stones associated with marked hyperoxaluria. Previously, we found that 1,2,3,4,6-penta-O-galloyl-Β-D-glucose (PGG), isolated from a traditional medicinal herb, reduced CaOx crystal …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:18:34