경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
bee 전체검색 결과
- 게시판
- 3개
- 게시물
- 34개
1/4 페이지 열람 중
대표논문 게시판 내 결과
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Bee venom phospholipase A2 ameliorates Alzheimer’s disease pathology in Aβ vaccination treatment without inducing neuro-infammation in a 3xTg-AD mouse model
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DOI https://doi.org/10.1038/s41598-018-35030-1 JOURNAL SCIENTIFIC REPORTS TITLE Bee venom phospholipase A2 ameliorates Alzheimer’s disease pathology in Aβ vaccination treatment without inducing neur…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2018-11-27 13:51:16 -
Bee venom phospholipase A2 ameliorates motor dysfunction and modulates microglia activation in Parkinson’s disease alpha-synuclein transgenic mice
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DOI 10.1038/emm.2016.49 JOURNAL Experimental & Molecular Medicine TITLE Bee venom phospholipase A2 ameliorates motor dysfunction and modulates microglia activation in Parkinson’s disease al…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2016-07-12 14:38:37 -
Neuroprotective effects of bee venom phospholipase A2 in the 3xTg AD mouse model of Alzheimer’s disease
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DOI 10.1186/s12974-016-0476-z JOURNAL Journal of Neuroinflammation TITLE Neuroprotective effects of bee venom phospholipase A2 in the 3xTg AD mouse model of Alzheimer’s disease AbstractB…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2016-01-18 09:49:17 -
Bee Venom Phospholipase A2, a Novel Foxp3+ Regulatory T Cell Inducer, Protects Dopaminergic Neurons by Modulating Neuroinflammatory Responses in a Mouse Model of Parkinson’s Disease
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Foxp3-expressing CD4+ regulatory T cells (Tregs) are vital for maintaining immune tolerance in animal models of various immune diseases. In the present study, we demonstrated that bee venom phospholipase A2 (bvPLA2) is the major BV compound capable of inducing Treg expansion and promotes the surviva…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2015-11-16 09:04:30 -
Neuro-protective effects of bee venom by suppression of neuroinflammatory responses in a mouse model of Parkinson's disease: Role of regulatory T cells
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Abstract In the present study, we sought to determine whether bee venom (BV) promotes the survival of dopaminergic (DA) neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson’s disease (PD). Treatment with BV prevented degeneration of DA neurons in the substanti…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2013-08-19 22:02:14
기타논문 게시판 내 결과
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The Responsiveness of Bee Venom Phospholipase A2 on Regulatory T Cells Correlates with the CD11c+CD206+Population in Human Peripheral Blood Mononuclear Cells
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Abstract: Bee venom phospholipase A2 (bvPLA2) has been reported to have therapeutic effects such as neuroprotection, anti-inflammation, anti-nociception, anti-cancer properties, caused by increasing regulatory T cells (Tregs). The mechanism of Tregs modulation by bvPLA2 has been …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:53:48 -
Targeting of adipose tissue macrophages by bee venom phospholipase A2 attenuates high-fat diet-induced obesity
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Abstract Background/objectives Adipose tissue macrophages (ATMs) exist in either the M1 or M2 form. The anti-inflammatory M2 ATMs accumulate in lean individuals, whereas the pro-inflammatory M1 ATMs accumulate in obese individuals. Bee venom phospholipase A2 (bvPLA2), a major co…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:41:51 -
Bee venom phospholipase A2 alleviates collagen‑induced polyarthritis by inducing Foxp3+ regulatory T cell polarization in mice
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The mechanism underlying bee venom (BV) therapy is still controversial, with opinions ranging from constituent-based pharmacological action to homeopathic-like activity. The purpose of this study was to examine whether BV phospholipase A2 (bvPLA2), an enzymatic component of BV, i…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2022-03-08 13:25:21 -
Bee Venom Phospholipase A2 Induces Regulatory T Cell Populations by Suppressing Apoptotic Signaling Pathway
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Abstract: Bee venom phospholipase A2 is a lipolytic enzyme in bee venom that catalyzes hydrolysis of the sn-2 ester bond of membrane phospholipids to produce free fatty acid and lysophospholipids.Current evidence suggests that bee venom phospholipase A2 (bvPLA2) induces regulatory T cell expansion…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-10-29 15:25:36 -
Bee Venom Phospholipase A2 Ameliorates Atherosclerosis by Modulating Regulatory T Cells
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Abstract: Atherosclerosis is a chronic inflammatory disease caused by lipids and calcareous accumulations in the vascular wall due to an inflammatory reaction. Recent reports have demonstrated that regulatory T (Treg) cells have an important role as a new treatment for atherosclerosis. This studys…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2020-10-29 15:11:47