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Anti-Inflammatory Applications of Melittin, a Major Component of Bee Venom: Detailed Mechanism of Action and Adverse Effects
새창
Abstract: Inflammation is a pervasive phenomenon triggered by the innate and adaptive immune systems to maintain homeostasis. The phenomenon normally leads to recovery from infection and healing, but when not properly phased, inflammation may cause immune disorders. Bee venom is a toxin that bees us…
최고관리자 2016-05-12 15:52:24 -
The therapeutic effects of tuberostemonine against cigarette smoke-induced acute lung inflammation in mice
새창
The therapeutic effects of tuberostemonine against cigarette smoke-induced acute lung inflammation in mice
최고관리자 2016-04-25 17:50:18 -
Therapeutic Effects of Bee Venom on Immunological and Neurological Diseases
새창
Abstract Bee Venom (BV) has long been used in Korea to relieve pain symptoms and to treat inflammatory diseases, such as rheumatoid arthritis. The underlying mechanisms of the anti-inflammatory and analgesic actions of BV have been proved to some extent. Additionally, recent clinical and experiment…
최고관리자 2015-08-27 14:53:35 -
Analgesic Effects of Bee Venom Derived Phospholipase A2 in a Mouse Model of Oxaliplatin-Induced Neuropathic Pain
새창
Abstract A single infusion of oxaliplatin, which is widely used to treat metastatic colorectal cancer, induces specific sensory neurotoxicity signs that are triggered or aggravated when exposed to cold or mechanical stimuli. Bee Venom (BV) has been traditionally used in Korea to treat various pain …
최고관리자 2015-08-27 14:51:46 -
Nicotinic Acetylcholine Receptors Mediate the Suppressive Effect of an Injection of Diluted Bee Venom into the GV3 Acupoint on Oxaliplatin-Induced Neuropathic Cold Allodynia in Rats
새창
Oxaliplatin, a platinum-based chemotherapy drug, often induces acute neuropathic pain, especially cold allodynia, even after a single administration. Subcutaneous injection of diluted bee venom (BV) into acupoints has been used to treat various pain symptoms in traditional oriental medicine. Althoug…
최고관리자 2015-08-27 14:33:44 -
Inhibitory effects of Stemona tuberosa on lung inflammation in a subacute cigarette smoke-induced mouse model
새창
Abstract Background: Stemona tuberosa has long been used in Korean and Chinese medicine to ameliorate various lung diseases such as pneumonia and bronchitis. However, it has not yet been proven that Stemona tuberosa has positive effects on lung inflammation. Methods: Stemona tuberosa extract (ST) …
최고관리자 2015-01-19 16:39:06 -
The effects of the standardized herbal formula PM014 on pulmonary inflammation and airway responsiveness in a murine model of cockroach allergen-induced asthma
새창
Abstract Ethnopharmacological relevance PM014 is a modified form of the Chung-Sang-Bo-Ha-Tang (CSBHT) herbal formula that has been used to treat chronic pulmonary diseases in Korea for centuries. Previously, we developed a formulation of PM014 based on a series of in vitro and in vivo screening eff…
최고관리자 2014-12-17 01:16:54 -
Cardioprotective effect of rhizomes of Acorus gramineus against isoproterenol-induced cardiac damage in pigs
새창
Abstract The present study was designed to evaluate the cardioprotective potential of water extract of rhizomes of Acorus gramineus (AGR) against isoproterenol (ISO)-induced myocardial infarction. Male pigs were orally administered with 250 or 500 mg/kg of AGR or with vehicle for 9 days, with concu…
최고관리자 2014-12-17 01:08:58 -
Effects of electroacupuncture on oxaliplatin-induced neuropathic cold hypersensitivity in rats
새창
Abstract This study investigated whether and how electroacupuncture (EA) attenuates cold hypersensitivity (allodynia) in a rat model of oxaliplatin-induced neuropathic pain. Cold allodynia [evaluated by immersing the tail into cold water (4 C) and measuring the withdrawal latency] was induced 3 day…
최고관리자 2014-12-17 01:06:54 -
The effects of maekmoondong-tang on cockroach extract-induced allergic asthma
새창
Abstract Maekmoondong-tang (MMDT) has long been used in Asian countries to treat respiratory diseases. However, the precise mechanisms underlying its effects on asthma are unknown. This study was conducted to evaluate the protective effects of MMDT in a cockroach allergen (CKA-)induced animal model…
최고관리자 2014-12-17 01:02:35