경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
for 전체검색 결과
- 게시판
- 2개
- 게시물
- 20개
2/2 페이지 열람 중
기타논문 게시판 내 결과
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Herbal formula, PM014, attenuates lung inflammation in a murine model of chronic obstructive pulmonary disease
새창
Abstract Chronic obstructive pulmonary disease (COPD), which is characterized by airway obstruction, leads to, as the two major forms of COPD, chronic bronchitis and emphysema. This study was conducted to evaluate the effects of herbal formula, PM014, in a murine model of COPD. Balb/c mice were tre…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 23:47:33 -
Safety and efficacy assessment of standardized herbal formula PM012
새창
Abstract Background: This study was conducted to evaluate the efficacy of the herbal formula PM012 on an Alzheimer's disease model, human presenilin 2 mutant transgenic mice (hPS2m), and also to evaluate the toxicity of PM012 in Sprague-Dawely rats after 4 or 26 weeks treatment with repeated o…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:43:52 -
Anti-diabetic effect of standardized herbal formula PM021 consisting of Mori Folium and Aurantii Fructus on type II diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats
새창
Abstract PM021, which consists of two herbal components, Mori Folium and Aurantii Fructus, is routinely used to treat diabetes in Korea. In this study, the anti-diabetic effect of PM021 on an animal model of developing type 2 diabetes of Otsuka Long-Evans Tokushima Fatty (OLETF) rats was investigat…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 21:29:03 -
TOXPO: TOXicogenomics knowledgebase for inferring toxicity based on POlymorphism
새창
Abstract Recently, many state-of-the-art omics technologies are being applied to systems toxicology research because evaluation of toxicity in pre-clinical trials is a big issue in the pharmaceutical industry. Now, genetic polymorphisms are also considered in systems toxicology because polymorphism…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 20:12:41 -
Screening of herbal medicines for the recovery of cisplatin-induced nephrotoxicity
새창
Abstract The goal of this study was to quantitatively determine the recovery effects of herbal medicines (HM) on the cisplatin-induced nephrotoxicity. In the present study, the recovery effects of 239 HM on HEK 293 cells that had been damaged by cisplatin were evaluated by a mitochondrial activity …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 19:10:56 -
Screening of herbal medicines for recovery of acetaminophen-induced nephrotoxicity
새창
Abstract This study was conducted to quantitatively evaluate the recovery effects of herbal medicines on acetaminophen-induced nephrotoxicity. In the present study, the recovery effects of 251 herb medicines on HEK 293 cells that had been damaged by acetaminophen were evaluated using an MTS assay. …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 18:47:23 -
THINKherb: The Herb INformation Knowledge base - The chip content database for herbal medicine
새창
Abstract Motivation: Herbal products are widely used in the field of medicine. The effect of herb is well-known in the field of medicine1. It is applied widely from simple pain controls to many severe diseases. Yet, due to shortage of scientific evidence on molecular mechanism of herbs, it had rema…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 18:33:40 -
The multi-herbal formula Guibi-tang enhances memory and increases cell proliferation in the rat hippocampus
새창
Abstract Guibi-tang (GBT) is a multi-herbal medicinal formula that has been used to treat amnesia in the traditional Korean medicine system for hundreds of years. In this study, we investigated the effects of GBT on learning and memory function in Wistar rats by using the foot shock passive avoidan…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 15:15:50 -
Closely Related G-protein-coupled Receptors Use Multiple and Distinct Domains on G-protein α-Subunits for Selective Coupling
새창
Abstract The molecular basis of selectivity in G-protein receptor coupling has been explored by comparing the abilities of G-protein heterotrimers containing chimeric Gα subunits, comprised of various regions of G i1α, Gtα, and Gqα, to stabilize the high affinity agonist binding state of serotonin,…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 13:59:38 -
Molecular basis for interactions of G protein βΓ subunits with effectors
새창
Abstract Both the α and βΓ subunits of heterotrimeric guanine nucleotide- binding proteins (G proteins) communicate signals from receptors to effectors. GβΓ subunits can regulate a diverse array of effectors, including ion channels and enzymes. Gα subunits bound to guanine diphosphate (Gα-GDP) inhi…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 12:53:29