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Screening of acetylcholinesterase inhibitors in herbal medicines
새창
Abstract The pathogenesis of Alzheimer’s disease (AD) has been linked to a deficiency in the brain neurotransmitter acetylcholine. Subsequently, acetylcholinesterase (AChE) inhibitors were used for the treatment of mild to moderate AD. The goal of this study was determine the candidate therapeutic…
최고관리자 2015-08-27 14:49:10 -
Nicotinic Acetylcholine Receptors Mediate the Suppressive Effect of an Injection of Diluted Bee Venom into the GV3 Acupoint on Oxaliplatin-Induced Neuropathic Cold Allodynia in Rats
새창
Oxaliplatin, a platinum-based chemotherapy drug, often induces acute neuropathic pain, especially cold allodynia, even after a single administration. Subcutaneous injection of diluted bee venom (BV) into acupoints has been used to treat various pain symptoms in traditional oriental medicine. Althoug…
최고관리자 2015-08-27 14:33:44 -
Efficacy of Acupuncture in Reducing Preoperative Anxiety: A Meta-Analysis
새창
1. IntroductionAnxiety prior to undergoing surgery is experienced by approximately 60–70% of adult patients [1]. The effects of reducing preoperative anxiety can be observed by estimating heart rate (HR), blood pressure (BP), and neuroendocrinological changes [2]. These effects can also be determine…
최고관리자 2015-08-27 13:59:24 -
Inhibitory effects of Stemona tuberosa on lung inflammation in a subacute cigarette smoke-induced mouse model
새창
Abstract Background: Stemona tuberosa has long been used in Korean and Chinese medicine to ameliorate various lung diseases such as pneumonia and bronchitis. However, it has not yet been proven that Stemona tuberosa has positive effects on lung inflammation. Methods: Stemona tuberosa extract (ST) …
최고관리자 2015-01-19 16:39:06 -
The effects of the standardized herbal formula PM014 on pulmonary inflammation and airway responsiveness in a murine model of cockroach allergen-induced asthma
새창
Abstract Ethnopharmacological relevance PM014 is a modified form of the Chung-Sang-Bo-Ha-Tang (CSBHT) herbal formula that has been used to treat chronic pulmonary diseases in Korea for centuries. Previously, we developed a formulation of PM014 based on a series of in vitro and in vivo screening eff…
최고관리자 2014-12-17 01:16:54 -
Expression levels of the hypothalamic AMPK gene determines the responsiveness of the rats to electroacupuncture-induced analgesia
새창
Abstract Background: Although electroacupuncture (EA) relieves various types of pain, individual differences in the sensitivity to EA analgesia have been reported, causing experimental and clinical difficulties. Our functional genomic study using cDNA microarray identified that 5'-AMP-activate…
최고관리자 2014-12-17 01:15:09 -
Cardioprotective effect of rhizomes of Acorus gramineus against isoproterenol-induced cardiac damage in pigs
새창
Abstract The present study was designed to evaluate the cardioprotective potential of water extract of rhizomes of Acorus gramineus (AGR) against isoproterenol (ISO)-induced myocardial infarction. Male pigs were orally administered with 250 or 500 mg/kg of AGR or with vehicle for 9 days, with concu…
최고관리자 2014-12-17 01:08:58 -
Effects of electroacupuncture on oxaliplatin-induced neuropathic cold hypersensitivity in rats
새창
Abstract This study investigated whether and how electroacupuncture (EA) attenuates cold hypersensitivity (allodynia) in a rat model of oxaliplatin-induced neuropathic pain. Cold allodynia [evaluated by immersing the tail into cold water (4 C) and measuring the withdrawal latency] was induced 3 day…
최고관리자 2014-12-17 01:06:54 -
Gyejigachulbu-Tang relieves oxaliplatin-induced neuropathic cold and mechanical hypersensitivity in rats via the suppression of spinal glial activation
새창
Abstract Activation of spinal glial cells plays a crucial role in the pathogenesis of neuropathic pain. An administration of oxaliplatin, an important anticancer drug, often induces acute neuropathic cold hypersensitivity and/or mechanical hypersensitivity in patients. Gyejigachulbu-tang (GBT), a h…
최고관리자 2014-12-17 01:04:56 -
The effects of maekmoondong-tang on cockroach extract-induced allergic asthma
새창
Abstract Maekmoondong-tang (MMDT) has long been used in Asian countries to treat respiratory diseases. However, the precise mechanisms underlying its effects on asthma are unknown. This study was conducted to evaluate the protective effects of MMDT in a cockroach allergen (CKA-)induced animal model…
최고관리자 2014-12-17 01:02:35