경희대학교 한의과대학 배현수 교수 연구실
Prof. Hyunsu Bae / College of Korean Medicine, Kyung Hee Univeristy, Seoul, Korea
of 전체검색 결과
- 게시판
- 1개
- 게시물
- 137개
14/14 페이지 열람 중
기타논문 게시판 내 결과
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The association of cholecystokinin-A receptor expression with the responsiveness of electroacupuncture analgesic effects in rat
새창
Abstract The purpose of this study is to determine whether the level of cholecystokinin (CCK) receptor expression causes the differences between the responder and non-responder to electroacupuncture mediated analgesic effects. Male Sprague-Dawley rats were stimulated at the Zusanli (ST36) acupoint …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 13:09:02 -
The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis
새창
Abstract Nuclear factor of activated T cells (NFAT) transcription factors regulate gene expression in lymphocytes and control cardiac valve formation. Here, we report that NFATp regulates chondrogenesis in the adult animal. In mice lacking NFATp, resident cells in the extraarticular connective tiss…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 13:01:10 -
Two amino acids within the helix of Gα(i1) mediate coupling with 5- hydroxytryptamine(1B) receptors
새창
Abstract We previously reported that residues 299-318 in Gα(i1) participate in the selective interaction between Gα(i1) and the 5-hydroxytryptamine(1B) (5- HT(1B)) receptor (Bae, H., Anderson, K., Flood, L. A., Skiba, N. P., Hamm, H. E., and Graber, S. G. (1997) J. Biol. Chem. 272, 32071-32077). Th…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 12:59:04 -
The α-helical domain of Gα(t) determines specific interaction with regulator of G protein signaling 9
새창
Abstract RGS proteins (regulators of G protein signaling) are potent accelerators of the intrinsic GTPase activity of G protein α subunits (GAPs), thus controlling the response kinetics of a variety of cell signaling processes. Most RGS domains that have been studied have relatively little GTPase a…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 12:55:39 -
Molecular basis for interactions of G protein βΓ subunits with effectors
새창
Abstract Both the α and βΓ subunits of heterotrimeric guanine nucleotide- binding proteins (G proteins) communicate signals from receptors to effectors. GβΓ subunits can regulate a diverse array of effectors, including ion channels and enzymes. Gα subunits bound to guanine diphosphate (Gα-GDP) inhi…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 12:53:29 -
Molecular determinants of selectivity in 5-hydroxytryptamine(1B) receptor-G protein interactions
새창
Abstract The recognition between G protein and cognate receptor plays a key role in specific cellular responses to environmental stimuli. Here we explore specificity in receptor-G protein coupling by taking advantage of the ability of the 5-hydroxytryptamine(1B) (5-HT(1B)) receptor to discriminate …
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 12:49:35 -
Mapping of effector binding sites of transducin α-subunit using Gαt/Gαi1 chimeras
새창
Abstract The G protein transducin has been an often-used model for biochemical, structural, and mechanistic studies of G protein function. Experimental studies have been limited, however, by the inability to express quantities of mutants in heterologous systems with ease. In this study we have made…
최고관리자 쪽지보내기 메일보내기 자기소개 전체게시물 2014-12-16 12:46:44